A clinicopathological study of interface dermatitis.
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Date
2014-07
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Abstract
Background: Interface dermatitis (ID) refers to a pattern of skin reaction
characterized by an inflammatory infiltrate that appears to obscure the dermoepidermal
junction when observed at low power examination and referred to as
lichenoid tissue reaction. A wide range of inflammatory skin diseases exhibits
interface change with considerable overlap of histological features. The aim of
the present study was to study the clinical features and microscopic features
of ID. Materials and Methods: The material for the present study consisted of
skin biopsy samples collected from patients attending the outpatient Department
of Dermatology. The study was conducted for a period of 3 years from 2007
to 2010. During this period, a total of 125 cases was studied. Results: In
the present study, a total of 125 cases of ID was studied which presented
clinically as papulosquamous disorders. Majority of the cases of ID were seen
in women (57.6%). Majority of ID were lichen planus (LP) and its variants
(63.2%). Clinicopathological concordance was seen in 109 cases (87.2%)
and discordance in 16 cases (12.8%). Conclusion: The mere presence of
an interface lichenoid inflammatory reaction should not be the sole criterion
for the diagnosis of LP or one of its many variants, as now seems to be the
case. A clinicopathologic correlation is absolutely essential for a conclusive
diagnosis of ID.
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Keywords
Interface dermatitis, lichen planus, lichenoid disorders
Citation
Hegde Vijaya Kumar, Khadilkar Urmila N. A clinicopathological study of interface dermatitis. Indian Journal of Pathology & Microbiology. 2014 Jul-sept 57 (3): 386-389.