Intraosseous angiolipoma of the frontal bone with a unique location: A clinical and pathological case illustration and review of the literature.

Abstract
Here, we report a case of a 16-year-old female patient was referred with scalp swelling and headache. Her neurological examination was normal and imaging of the skull revealed a well-defi ned lytic lesion measuring 15 mm × 6 mm to the right of the frontal bone. She was operated on with a prediagnosis of Langerhans cell histiocytosis. A wide excision with negative margins was made and the defect was reconstructed with a titanium plate. Subsequently, the lesion was histopathologically diagnosed as an angiolipoma of the frontal bone. The postoperative period was uneventful and she remained well during 1-year follow-up with no evidence of recurrence. Angiolipomas are rare benign lipomatous lesions located mostly in subcutaneous tissue of the forearm or trunk and frequently occur before puberty or in young adults. They are not common in bones. To the best of our knowledge, this is the fi rst angiolipoma of the frontal bone reported.
Description
Keywords
Angiogenesis, intraosseous angiolipoma, mast cells, skull bone
Citation
Atilgan Alev Ok, Terzi Aysen, Agildere Muhtesem, Caner Hakan, Ozdemir B Handan. Intraosseous angiolipoma of the frontal bone with a unique location: A clinical and pathological case illustration and review of the literature. Indian Journal of Pathology & Microbiology. 2014 Apr-Jun 57 (2): 301-304.