Cutaneous amyloidosis at the site of insulin injection with coexistence of acanthosis nigricans.
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Date
2014-01
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Abstract
Skin is one of the important organs affected by amyloidosis which is characterized
by extracellular deposition of fibrillary proteins having homogenous, eosinophilic
on routine staining with distinct tinctorial properties. Nodular cutaneous
amyloidosis is rare and may affect dermis, subcutis and also vascular walls.
Nodular amyloid deposits in the deeper dermis occurring at the site of insulin
injection are a rare observation, which is described here. This description
indicates that cutaneous amyloidosis may be associated with local subcutaneous
injections of insulin and may clinically mimic a neoplasm or lipodystrophic lesion.
Description
Keywords
Acanthosis nigricans, birefringence, cutaneous amyloid, insulin
Citation
Nandeesh Bevinahalli N, Rajalakshmi T, Shubha B. Cutaneous amyloidosis at the site of insulin injection with coexistence of acanthosis nigricans. Indian Journal of Pathology & Microbiology. 2014 Jan-Mar 57 (1): 127-129.