Krukenberg tumor in a young woman: A rare presentation.
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Date
2014-01
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Abstract
Krukenberg tumors mostly occur after 40 years. Metastatic ovarian tumors
in young age are very rare and reported to be 2% of all the cases. Thirty
percent of all ovarian neoplasms occurring during childhood and adolescence
are malignant. A 25-year-old woman, parity- 2, presented with abdominal
distension, pain in abdomen and amenorrhea. On examination, 18 weeks
lump was palpable, fi rm to hard in consistency, non-tender and mobile. On
ultrasonography bilateral ovarian tumors were reported, without any peritoneal
free fl uid. Total abdominal hysterectomy with bilateral salpingo-oophorectomy
was performed. Microscopic examination revealed signet ring cells with
glandular differentiation, diffusely invading the ovarian parenchyma. Tumor
cells exhibited strong, diffuse immunopositivity for CEA with focal strong
immunopositivity for CK7 and CK20 and immunonegativity for SATB2. Diagnosis
of Krukenberg tumor was made. Endoscopic biopsy confi rmed the diagnosis
of adenocarcinoma stomach.
This case is reported because of its rarity in younger age group.
Description
Keywords
CEA, CK7, CK20, immunohistochemistry, krukenberg, SATB2
Citation
Hatwal Deepa, Joshi Chitra, Chaudhari Sheela, Bhatt Pawan. Krukenberg tumor in a young woman: A rare presentation. Indian Journal of Pathology & Microbiology. 2014 Jan-Mar 57 (1): 124-126.