Chronic lymphocytic leukemia developing in a case of chronic myelogenous leukemia - accelerated phase: A rare case with review of the literature.

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Date
2013-07
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Abstract
Chronic myelogenous leukemia (CML) and chronic lymphocytic leukemia (CLL) are two different and common hematological neoplasms. Their coexistence is rare, especially CLL developing in a patient of CML. Till date, only a few cases are reported and all had chronic myeloid leukemia - chronic phase earlier. We report the first case of CLL developing in a patient initially diagnosed in an accelerated phase of chronic myeloid leukemia. The clonality of both CML and CLL was proven by cytogenetic, molecular and flow cytometric studies.
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Keywords
Bone marrow, chronic lymphocytic leukemia, chronic myelogenous leukemia, flow cytometry, imatinib
Citation
Kumar Narender, Ahluwalia Jasmina, Malhotra Pankaj, Sachdeva Man Updesh Singh. Chronic lymphocytic leukemia developing in a case of chronic myelogenous leukemia - accelerated phase: A rare case with review of the literature. Indian Journal of Pathology & Microbiology. 2013 Jul-Sept 56 (3): 303-305.