One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions.
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Date
2013-09
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Abstract
Macular edema is a significant cause of vision loss in patients
with central retinal vein occlusions and branch retinal vein
occlusions. Vascular endothelial growth factor (VEGF) appears
to be a key factor in the pathogenesis of this disease. Anti‑VEGF
therapy, such as intravitreal ranibizumab provides an effective
treatment against vision‑threatening macular edema. We report
three patients of retinal vein occlusion with macular edema
who demonstrated overnight resolution of macular edema
following treatment with intravitreal ranibizumab (0.5 mg).
3D optical coherence tomography (Optovue) was used as
a tool for comparison of the macular thickness before and
after treatment. The significant reductions in the central
foveal thickness demonstrated in these patients one night
after intravitreal injections could have significant influence
on modifying current treatment protocols. Early treatment of
macular edema related to retinal venous occlusive disease with
anti‑VEGF injections could result in faster visual rehabilitation
in these patients.
Description
Keywords
Macular edema, optical coherence tomography, ranibizumab, retinal vein occlusion, vascular endothelial growth factor
Citation
Verma Lalit, Chakravarti Arindam, Gupta Avnindra, Prakash Smriti. One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions. Indian Journal of Ophthalmology. 2013 Sep; 61(9): 528-530.