Paraneoplastic autoimmune multiorgan syndrome (paraneoplastic pemphigus) with unusual manifestations and without detectable autoantibodies.
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Date
2014-07
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Abstract
We describe a patient with paraneoplastic autoimmune multiorgan syndrome (PAMS)
secondary to a lymphoblastic T‑ cell lymphoma who presented with a lichenoid dermatitis and
vitiligo, later developing bronchiolitis obliterans and autoimmune hepatitis. Notably, he had no
detectable autoantibodies. The development of vitiligo and autoimmune hepatic involvement
probably indicate a role for cytotoxic T‑ cell lymphocytes in the pathogenesis of this syndrome.
Description
Keywords
Autoimmune diseases, paraneoplastic syndromes, precursor T‑Cell lymphoblastic leukemia‑lymphoma, lichenoid eruptions
Citation
Sanz-Bueno Jimena, Cullen Daniella, Zarco Carlos, Vanaclocha Francisco. Paraneoplastic autoimmune multiorgan syndrome (paraneoplastic pemphigus) with unusual manifestations and without detectable autoantibodies. Indian Journal of Dermatology, Venereology and Leprology. 2014 Jul-Aug; 80(4): 328-330.