A new occlusive patch test system comparable to IQ and Finn chambers.
Loading...
Date
2014-07
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Background: A good patch test system should have good adhesion and contact, and
minimal leakage; Finn and IQ patch test system have these properties but are expensive.
Aims: To develop a new cost‑effective occlusive patch test system that had good contact with
the skin and was non‑irritant. Methods: The system (designated Chamber X) was fabricated
using a semi‑permeable tape and a flexible virgin plastic chamber. Chamber X was developed
by (i) selecting adhesive tape based on its non irritancy and adhesive potential (ii) testing plastic
chamber material for its skin irritancy (iii) testing the assembled system against Finn, IQ and
locally available chambers for irritancy, contact, leakage and occlusivity. Results: Chamber
X showed better occlusion than IQ, Finn and locally available chambers and was comparable
to, (P > 0.05) IQ and Finn in terms of irritancy, contact and leakage. Conclusions: The results
demonstrate that the Chamber X offers a cost effective patch test system comparable to IQ
and Finn chambers in terms of safety, adhesion, leakage and occlusivity.
Description
Keywords
Allergy testing, Chamber X, clinical trial, Finn chambers, human patch test, IQ chambers
Citation
Merchant Shaziya Z Sajun, Vaidya Ashlesha D, Salvi Anjali, Joshi Rajiv S, Mohile Rashmikant B. A new occlusive patch test system comparable to IQ and Finn chambers. Indian Journal of Dermatology, Venereology and Leprology. 2014 Jul-Aug; 80(4): 291-295.