Thalidomide induced xerosis: an unwanted reaction.
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Date
2014-07
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Abstract
A 59-year-old male exhibited anemia for evaluation. Endoscopy was diagnostic of gastric antral vascular ectasia. He was given a trial of thalidomide after informing about the adverse effects. After starting thalidomide at 100 mg/day, his hemoglobin (Hb) improved. Post 1 month of therapy his Hb normalized, but he developed xerosis. He was given symptomatic treatment, but did not improve. Thalidomide was suspected to cause xerosis, it was discontinued for a month and post-discontinuation of drug he is symptom free for past 8 months. This paper reports a rare case of thalidomide induced xerosis with dermatological and neurological involvement.
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Keywords
Anemia, Gastric antral vascular ectasia, Thalidomide, Xerosis
Citation
Kamath Nagesh, Shetty Anurag, Singh Harneet, Shetty Shiran, Sirasanagandla Srinivasa Rao. Thalidomide induced xerosis: an unwanted reaction. International Journal of Basic & Clinical Pharmacology. 2014 Jul-Aug ; 3(4): 732-735.