A drug will not function unless it is bound to a receptor: a longstanding confusion in basic pharmacology.
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Date
2013-11
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Abstract
The disparity between the general definition of a ‘drug’ and the wide-spread mechanism of actions of receptor-dependent drugs may often mislead to believe that a drug-receptor interaction is always indispensable for a drug to exert its action. This short review is intended to rectify this basic misconception in pharmacology with the aid of a list of examples of several receptor-independent drugs in context to their mode of actions.
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Receptor-independent drugs, Osmotic diuretics, Keratolytic agent, Chelating agents, Surfactants, Antacid, Protectants and adsorbents, Sucralfate, Laxatives, Cholestyramine, NAC
Citation
Saha Partha S. A drug will not function unless it is bound to a receptor: a longstanding confusion in basic pharmacology. International Journal of Basic & Clinical Pharmacology. 2013 Nov-Dec; 2(6): 693-695.