Current state of pharmacology and therapeutics in irritable bowel syndrome with special reference to brain-gut axis.
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Date
2013-03
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Abstract
Irritable bowel syndrome (IBS), principal morbidity being visceral hypersensitivity, consumes significant speciality gastroenterologic and general practitioner’s care. The complex etiology perhaps varying among the patients makes therapeutic address very challenging. Continuous researches on neurophysiological aberrations in IBS have continued. The drugs and the neurophysiological understanding with regard to addressing visceral hypersensitivity are relevant to be appraised. The translation of research wisdom into clinical practice may be facilitated by gastroenterology experts. The issues of effectiveness of the options in general and in particular patients may thus be addressed.
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Keywords
Irritable bowel syndrome, Visceral hypersensitivity, Brain-gut axis, Neurotransmitters
Citation
Mishra Suryaprakash, Singh Alok, Pandey B L. Current state of pharmacology and therapeutics in irritable bowel syndrome with special reference to brain-gut axis. International Journal of Basic & Clinical Pharmacology. 2013 Mar-Apr; 2(2): 122-129.