Syphilis and human immunodeficiency virus co-infection among pregnant women in Nigeria: prevalence and trend.
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Date
2014-07
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Abstract
Pregnant women are at increased risk of sexually transmitted infections (STIs) due to
physiological changes that accompany pregnancy, such as congestion of the cervix,
edema of the vaginal mucosa, and alterations in the vaginal flora. Syphilis and HIV are
both transmitted sexually and so it is not surprise that a substantial number of people are
infected with both agents. The rate of HIV and syphilis co-infection varies depending on
the prevalence of both infections in the community or the patient group being studied,
along with individual risk factors. 1913 apparently healthy pregnant women were recruited
for the study after obtained their consent. Detection of HIV p24 antigen and antibodies to
HIV1/2 was screened for using BIO-RAD in-vitro diagnostic enzyme immunoassay;
syphilis was screen for using DIA-PRO in-vitro diagnostic Bio-probes enzyme
immunoassay for the determination of antibodies to Treponema pallidum. Age group 26-30 had highest prevalence of HIV and VDRL in the study years, a decreasing trend was
observed in the prevalence of HIV and syphilis infection within the study years. Seroprevalence
of HIV and VDRL were 63(3.29%) and 03(0.16%) respectively. The
prevalence of HIV and VDRL co-infection was 01(0.05%) observed in age group 26-30.
This present study clearly documents a relatively declined in sero-prevalence of HIV and
VDRL within the consecutive three years of study, this reflects the level of HIV and VDRL
in the general population.
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Keywords
Syphilis, human immunodeficiency virus, mode of transmission
Citation
Omisakin C T, Esan A J, Fasakin K A, Owoseni M F, Ojo-Bola O, Aina O O, Omoniyi D P. Syphilis and human immunodeficiency virus co-infection among pregnant women in Nigeria: prevalence and trend. International STD Research & Reviews. 2014 Jul-Dec; 2(2): 94-100.