Assessment Of feto maternal hemorrhage in antenatal period in Indian females – need of modifications in Anti D prophylaxis in India.

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Date
2012-07
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Abstract
Objective: -To assess Feto maternal Hemorrhage in pregnant Indian Females. Method: - 516 consecutive antenatal patients attending the Fetal Medicine Department of Vadilal Sarabhai General hospital under NHL Municipal Medical College, Ellis Bridge, Ahmadabad were analyzed for Feto maternal Hemorrhage by Kleihauer Betke test after taking informed consent. Result: - All the 516 antenatal patients including those who underwent invasive procedures like Chorionic villus sampling, Amniocentesis, Amnioinfusion and Intrauterine blood transfusion had Feto maternal Hemorrhage less than 2 ml. Conclusion: - Study shows that Feto maternal hemorrhage in Indian women is very insignificant even after invasive procedures. Feto maternal Hemorrhage has special importance in Rh Negative Women, carrying an Rh positive fetus.FMH can lead to isoimmunization leading to a wide spectrum of antenatal and postnatal fetal complications ranging from anemia to stillbirth. Answer to this is Antenatal Anti –D prophylaxis which is not a standard practice in our setup due to high cost of Anti D. As we have found FMH to be less than 2 ml even a dose of 50 microgram can suffice if given at 26 and 32 weeks of gestation to prevent isoimmunization thus reducing the cost and encouraging the practice of Antenatal Anti D prophylaxis.
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Andhra Pradesh, Bacteriological Profile, Antibiotic Resistance, Septicaemia, Blood culture
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Bamniya Jaishree, Vaishnav Gunvant, Panchal Divyesh, Vaishnav Jolly. Assessment Of feto maternal hemorrhage in antenatal period in Indian females – need of modifications in Anti D prophylaxis in India. National Journal of Integrated Research in Medicine. 2012 Jul-Aug; 3(3): 111-115.