The study of karyotypes in patients with congenital heart diseases of Gujarat State.
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Date
2012-07
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Abstract
Introduction: Congenital heart disease (CHD) is the most common of all the birth defects and is a leading cause of mortality in the 1st year of life. Congenital heart disease can be related to chromosomal aberrations and mutation of single gene. Material and Method: In this study a total of 24 confirmed cases of CHD were considered of age ranging from Day 1 to 15 years. A prior Written consent was taken from the parents of these patients. The relevant clinical data, important investigations and blood samples where collected. A conventional cytogenetic study was performed on the 24 selected patients. Results: Out of 24 patients 1 patient showed a chromosomal abnormality in the form of trisomy 21. Conclusion: Hence the present study was carried out as a Continued research on the genetic cause of congenital heart diseases and to augment our understanding of the mechanisms underlying the normal and abnormal development of the cardiac structures.
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Keywords
Congenital heart disease, Karyotype
Citation
Modasia Umesh P, Kodiyatar Bhavin B, Oza Sunil. The study of karyotypes in patients with congenital heart diseases of Gujarat State. National Journal of Integrated Research in Medicine. 2012 Jul-Aug; 3(3): 33-35.