Antimicrobial and Antioxidant activity of leaf and flower extract of Caesalpinia pulcherrima, Delonix regia and Peltaphorum ferrugineum.
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Date
2013-08
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Abstract
The present study was undertaken to determine antimicrobial and antioxidant activities of leaf and flower extracts
of Caesalpinia pulcherrima, Delonix regia and Peltaphorum ferrugineum. Antimicrobial activity was tested
against Staphylococcus aureus, Salmonella typhi, Candida albicans and Cryptococcus neoformans by Agar well
diffusion assay. Antioxidant activity was determined by DPPH free radical scavenging assay, ABTS free radical
scavenging assay, Ferric reducing assay and Total antioxidant capacity determination. Total phenolic content of
extracts was estimated by Folin-Ciocalteau Reagent method. S. typhi and C. neoformans were susceptible to
extracts to greater extent than S. aureus and C. albicans among bacteria and fungi respectively. Except C.
pulcherrima extract, the leaf extracts were more effective in inhibiting bacteria than flower extracts. Leaf extracts
have shown high antifungal activity than flower extracts. The extracts have shown dose dependent scavenging of
DPPH and ABTS radicals. Scavenging of ABTS radicals was more efficient than that of DPPH radicals as
revealed by low IC50 values. All leaf extracts except C. pulcherrima displayed stronger scavenging activities
than flower extracts. Similar results were observed in ferric reducing assay and total antioxidant capacity
determination. Total phenolic content was found to be higher in leaf extracts (except C. pulcherrima) than flower
extracts. A correlation has been observed between phenolic content of leaf and flower extracts and the
antioxidant activity. A marked antimicrobial and antioxidant activity of leaf and flower extracts was observed
which may be attributed to the presence of phenolic compounds and other phytochemicals. The plants can be
used to control infectious diseases and oxidative damage.
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Keywords
Caesalpinia pulcherrima, Delonix regia, Peltaphorum ferrugineum, Antimicrobial, Antioxidant
Citation
Vivek M N, Swamy H C Sachidananda, Manasa M, Pallavi S, Kambar Yashoda, Asha M M, Chaithra M, Kekuda T R Prashith, Mallikarjun N, Onkarappa R. Antimicrobial and Antioxidant activity of leaf and flower extract of Caesalpinia pulcherrima, Delonix regia and Peltaphorum ferrugineum. Journal of Applied Pharmaceutical Science. 2013 Aug; 3(8): 64-71.