Anti-dermatophytic activity of some traditionally used medicinal plants of North Karnataka Region.
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Date
2013-02
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Abstract
To find the potentiality of the following medicinal plants for their anti dermatophytic property. Agar and broth
dilution methods, Leaf extracts of Cassia occidentalis, Cassia tora, Lawsonia inermis, Xanthium strumarium
and Caesalpinia bonducella with various solvents viz., methanol, alcohol, acetone, acetone, petroleum ether,
chloroform and ethyl acetate were evaluated for antidermatophytic activity against human pathogenic fungi. In
agar and broth dilution methods, all extracts showed antifungal activity even at minimum inhibitory
concentrations (MICs) and minimum fungicidal concentrations (MFCs). The most biologically active extract
was found to be ethyl acetate leaf extract of C. bonducella, which inhibited all test fungi with time and dose
dependent activity. This plant extract retarded the growth of all the organisms at 10000 μg/ml up to 30 days and
beyond. It is further suggested for detail investigation of active constituents of the plants used in the present.
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Antidermatophytic activity, solvent extracts, traditional medicinal plants, skin diseases, human pathogenic fungi
Citation
Sagar Kavitha, Vidyasagar G M. Anti-dermatophytic activity of some traditionally used medicinal plants of North Karnataka Region. Journal of Applied Pharmaceutical Science. 2013 Feb; 3(2): 77-83.