Synthesis and biological evaluation of 2,4,5-triphenyl-1H-imidazole-1-yl Derivatives.
Loading...
Date
2012-07
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
In the present investigation, our aim of synthesis is to find a molecule having multi drug
treatment means the drug which resists the inflammation produce due to microbial infection. So,
2,4,5-triphenyl-1H-imidazole-1-yl derivatives were synthesized and tested for their antiinflammatory
activity in-vitro using Phenylbutazone as a reference drug and antimicrobial activity
using clotrimazole and ciprofloxacin as a standard drug. Compound 6b was found to be the most
potent derivative of the series.
Description
Keywords
Triphenyl-Imidazole, Anti-inflammatory, Antimicrobial, Multidrug
Citation
Zala Shailesh P, Badmanaban R, Sen Dhrubo Jyoti, Patel Chhaganbhai N. Synthesis and biological evaluation of 2,4,5-triphenyl-1H-imidazole-1-yl Derivatives. Journal of Applied Pharmaceutical Science. 2012 July; 2(7): 202-208.