Erythrocytes as carrier for drugs, enzymes and peptides.
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Date
2012-04
Journal Title
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Abstract
Erythrocytes are potential biocompatible carriers for different drugs, peptide molecules
and different enzymes. Now a day the method that is used for encapsulation of pharmaceuticals
into the erythrocytes mainly based on the hypo-osmotic dialysis. Encapsulation of these drugs or
enzymes or peptides into erythrocytes significantly changes the pharmacokinetic properties of
drugs in both animals and humans, enhancing liver and spleen uptake and targeting the reticuloendothelial
system. By the encapsulation of these into erythrocytes can be applied as targeted
drug delivery systems. Erythrocytes are successful as carrier systems for different drugs, enzymes
and peptide molecules. The result after using drug encapsulated in erythrocytes is more compared
to the free form of the drug.
Description
Keywords
Drug loading methods, carrier erythrocytes, Applications, Drugs, Enzymes, Peptides
Citation
Ravilla Srinu, Chandu Babu Rao, Nama Sreekanth, Nagaveni B. Erythrocytes as carrier for drugs, enzymes and peptides. Journal of Applied Pharmaceutical Science. 2012 Apr; 2(4): 166-176.