Anti-staphylococcal and antifungal substances produced by endospore-forming bacilli.
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Date
2012-04
Authors
Oliveira, V F
Abreu, Y J L
Fleming, L R
Nascimento, J S
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Journal ISSN
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Abstract
Some bacteria and fungi are related to deterioration and also transmission of foodborne
diseases, emphasizing the need to search new substances that may act in the treatment and
prevention of the illnesses transmitted by food. Strains from genus Bacillus produce a variety of
substances with inhibitory activity that range from antibiotics to bacteriocins. In this work, three
strains, identified as B. pasteurii (Pes1) and B. insolitus (Mam2 and Ame3) presented inhibitory
action against staphylococcal strains isolated from food. Out of the 33 strains tested, 31 (94.0%)
were inhibited by at least one of three main Bacillus producer strains, being most of them
inhibited by strain Pes1, that also was able to inhibit filamentous fungi related to food spoilage.
The antimicrobial substances produced by Pes1, Mam2 and Ame3 showed to be resistant to
proteolytic enzymes, suggesting these substances have not an active proteinaceous compound, as
typical bacteriocins. New studies are being performed to extract and characterize these
antimicrobial agents to evaluate their potential application in biological control of
microorganisms related to spoilage food and foodborne diseases.
Description
Keywords
antimicrobial substances, antifungal, anti-staphylococcal, biological control application, endospore-forming bacilli
Citation
Oliveira V F, Abreu Y J L, Fleming L R, Nascimento J S. Anti-staphylococcal and antifungal substances produced by endospore-forming bacilli. Journal of Applied Pharmaceutical Science. 2012 Apr; 2(4): 154-157.