Phytochemical screening and antibacterial activity of Gymnema sylvestre (Retz) R . Br ex. Schultes and Morinda pubescens J.E. Smith var. pubescens.
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Date
2012-01
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Abstract
Two medicinal plants namely Gymnema sylvestre and Morinda pubescens var.
pubescens were screened for potential antibacterial activity against Staphylococcus aureus,
Klebsiella pneumoniae, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa and
Salmonella typhi. The antibacterial activity was determined in petroleum ether, chloroform,
acetone, methanol and aqueous extracts using disc diffusion method. The chloroform and
methanol extract of leaf of Gymnema sylvestre showed highest inhibition against Escherichia coli
and Klebsiella pneumoniae respectively; whereas, acetone extract of Morinda pubescens var.
pubescens leaf exhibited maximum inhibition against Pseudomonas aeruginosa. Phytochemical
screening revealed the presence of alkaloids, flavonoids, phenols, tannins, and terpenoids. The
results of these studies revealed most valuable information and also support the continued
sustainable use of these plants in traditional systems of medicine.
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Gymnema sylvestre, Morinda pubescens var. pubescens, antibacterial activity, disc diffusion method
Citation
Murugan M, Mohan V R, Thamodharan V. Phytochemical screening and antibacterial activity of Gymnema sylvestre (Retz) R . Br ex. Schultes and Morinda pubescens J E Smith var pubescens. Journal of Applied Pharmaceutical Science. 2012 Jan; 2(1): 73-76.