Facts on inhaled Insulin.
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Date
2011-12
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Abstract
Until today, diabetic patients who need insulin to manage their disease had only one
way to treat their condition but Exubera is an inhaled powder form of recombinant human insulin
(rDNA) for the treatment of adult patients with type 1 and type 2 diabetes. American and
European Drug Agencies (FDA and EMEA) approved the first pulmonary delivered version of
insulin (Exubera®) for diabetic patients and hope that the availability of inhaled insulin will offer
more options to patients for better control of their blood sugars. The safety and efficacy of
Exubera has been studied in approximately 2500 adult patients with type 1 and type 2 diabetes. In
clinical studies, Exubera reached peak insulin concentration more quickly than some insulins,
called regular insulin, administered by an injection. Side effects associated with Exubera therapy
seen in clinical trials included cough, shortness of breath, sore throat, and dry mouth. Exubera is
not to be used for the patients who smoke or if you recently quit smoking (within the last 6
months). Exubera is not recommended in patients with asthma, bronchitis or emphysema. The
main objective of this review is to elucidate the advantages and adverse events of inhaled insulin.
Description
Keywords
Asthma, Bronchitis, Emphysema, Exubera, inhaled insulin
Citation
Gowtham T, Khan P Rafi, Chand K Gopi, Nagasaraswathi M. Facts on inhaled Insulin. Journal of Applied Pharmaceutical Science. 2011 Dec; 1(10): 18-23.