Beneficial health effects of rutin supplementation in patients with diabetes mellitus.
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Date
2011-10
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Abstract
Flavonoids, dietary antioxidant compounds may offer some protection against earlystage
diabetes mellitus and its associated complications. The present study aimed to evaluate the
effect of rutin on overall health of patients with diabetes mellitus. The effects of rutin were tested
by using it as a supplement with their regular medications. The total trial period was of 120 days
conducted with a gap of 30 days each. It consisted of 30 patients aging between 40-50 years,
having diabetes mellitus since last 5 years. These patients were given Rutin Tablets for 60 days.
Fasting Blood Sugar (FBS), Body Mass Index (BMI), blood pressures, lipid profile, serum urea
and creatinine, electrolytes, SGOT (serum glutamic oxaloacetic transaminase), SGPT (serum
glutamic pyruvic transaminase) and Alkaline phosphatase (ALP) were measured at baseline and
then after every 30 days. Rutin tablets were stopped for next 60 days. All of above parameters
were again measured on 90th and 120th day. The results showed that rutin decreased the levels of
FBS, systolic and diastolic blood pressure, HDL, Serum Urea and creatinine significantly
(P<0.05), whereas significant increase (P<0.05) in TGL, HDL, VLDL were seen. Decrease in
the level of SGOT, SGPT, ALP and BMI is not significant.
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Keywords
Rutin, SGPT, SGOT, ALP, Lipid Profile
Citation
Sattanathan K, Dhanapal C K, Umarani R, Manavalan R. Beneficial health effects of rutin supplementation in patients with diabetes mellitus. Journal of Applied Pharmaceutical Science. 2011 Oct; 1(8): 227-231.