Analgesic activity of ethanolic extract of roots of Prosopis cineraria (l.) Druce.
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Date
2011-10
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Abstract
Prosopis cineraria (L.) Druce is a deep rooted, nitrogen fixing, multipurpose tree
endemic to the hot deserts of India. Its synonym is Prosopis spicigera. It belongs to the family
Leguminosae and subfamily Mimosoideae. In view of its medicinal importance, the present
research was focused on the analgesic properties of roots of P. cineraria by in vitro approach in
rats. The analgesic activity of root of Prosopis cineraria was studied using hot-plate method and
tail-immersion method in rats. Doses of the ethanolic extract of 200mg/kg & 300mg/kg, orally
were selected for analgesic activity. The extract at all the doses used and the Diclofenac sodium
significantly inhibited both the analgesic activity for hot plate and tail immersion method. The
present study demonstrates the potential analgesic effect of ethanolic extracts of Prosopis
cineraria roots. The dose of 200mg/kg b.w is very effective than 300mg/kg b.w in both above
pharmacological models.
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Keywords
Prosopis cineraria, Roots, Analgesic, Hot plate and Tail immersion
Citation
Kumar Arvind, Yadav Sanjay Kumar, Singh Satyawan, Pandeya S N. Analgesic activity of ethanolic extract of roots of Prosopis cineraria (l.) Druce. Journal of Applied Pharmaceutical Science. 2011 Oct; 1(8): 158-160.