Antidepressant activity of spirulina platensis in experimentally induced dipression in mice.
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Date
2014-04
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Abstract
The spray dried powder of Spirulina platensis was used to treatment of depression in different doses (100mg/kg, 200 mg/kg and 400 mg/kg) and
Impramine (15mg/kg) as standard drug in experimental animal models like Forced swim test in mice, Tail suspension test in mice, Clonidine induced aggression
behaviour in mice test, L-dopa induced hyper activity and aggressive behavior in mice, 5-HT induced head twitches in mice, From all the experimental model results
were observed that the Spirulina platensis was possess the dose dependent anti depressant activity.
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Keywords
Spirulina platensis, Depression, Imipramine, 5-HT, L-dopa, Clonidine
Citation
Suresh D, Madhu M, Saritha Ch, Raj kumar V, Shankaraiah P. Antidepressant activity of spirulina platensis in experimentally induced dipression in mice. International Journal of Research and Development in Pharmacy and Life Sciences. 2014 Apr-May; 3(3): 1026-1035.