Enzymes in clinical medicine: An overview.
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Date
2013-10
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Abstract
Enzymes are biocatalysts and because of their remarkable properties, they are extensively used in medical diagnosis. Researches in the last two decades have concentrated more on enzymes such as creatine kinaseāMB, alanine transaminase, aspartate transaminase, acid phosphatase, alkaline phosphatase etc. for clinical applications. Enzymes are the preferred markers in various disease states such as myocardial infarction, jaundice, pancreatitis, cancer, neurodegenerative disorders, etc. They provide insight into the disease process by diagnosis, prognosis and assessment of response therapy. Even though the literature on the use of enzymes in various disease conditions has accumulated, a comprehensive analysis is lacking and hence this review.
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Keywords
Biomarkers, Biosensors, Diagnostics, Enzymes
Citation
Hemalatha Thiagarajan, UmaMaheswari Thiagamoorthy, Krithiga Gunasekaran, Sankaranarayanan Palavesam, Puvanakrishnan Rengarajulu. Enzymes in clinical medicine: An overview. Indian Journal of Experimental Biology. 2013 Oct; 51(10): 777-788.