Non secretory multiple myeloma – a case report.

Abstract
A rare variant of multiple mieloma, non-secretory multiple myeloma (NSM), is reported. Diagnosis of NSM is made by presentations of lytic bone lesions with bone pain, anemia, slight hypercalcemia, good renal function, negative results of protein and immunoelectrophoresis detecting monoclonal gammopathy, and positive clonal proliferation of plasma cells and atypical plasma cells in bone marrow biopsy. Immunophenotypic study resulted negative pan-B cell antigens and positive CD 79a. Patient condition was improved after institution of combination chemotherapy and 1 year afterward.
Description
Keywords
multiple myeloma, non-secretory multiple myeloma, diagnosis, management
Citation
Taroeno-Hariadi Kartika W, Purwanto Ibnu, Kurnianda Johan, Mangunsudirjo Sagiri, Harijadi A, Puntodewo Puntodewo. Non secretory multiple myeloma – a case report. Medical Journal of Indonesia. 2007 Oct; 16(4): 257-261.