Giant verruca vulgaris: a case report.

Haroen, Mona S; Purba, Herliyani M; Kartadjukardi, Eddy; Sularsito, Sri A

Giant verruca vulgaris: a case report.

Date

2009-04

Authors

Abstract

Common wart is the most frequent clinical lesion caused by human papillomaviruses (HPVs). Giant, chronic, isolated, and solitary lesion is uncommon. We reported a case of giant verruca vulgaris in a 66 year-old man on left dorsal pedis that slowly enlarged and hardened in 10 years. It was a solitary hyperkeratotic verruca vulgaris, grey brownish in color, circumscribe, round, and 3x2.4x0.4 cm in size. Histopathologic examination revealed compact hyperkeratosis/orthokeratosis, many koilocytes in the granular and upper spinous layer, acanthosis, and elongated rete ridges that were pointing radially toward the center of the lesion. Polymerase chain reaction (PCR) and in situ hybridization failed to identify HPV DNA. The patient was successfully treated with salicylic acid 40% ointment.

Keywords

papilloma viruses, hyperkeratosis, orthokeratosis

Citation

Haroen Mona S, Purba Herliyani M, Kartadjukardi Eddy, Sularsito Sri A. Giant verruca vulgaris: a case report. Medical Journal of Indonesia. 2009 Apr; 18(2): 135-138.