Family history of hypertension is associated with exaggerated cardiovascular reactivity to mental, but not to physical test.
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Date
2010-05
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Abstract
Aim To investigate whether normotensive young adults with family history of hypertension demonstrate exaggerated
cardiovascular responses to both mental and physical stimuli as compared to normotensive young adults without
family history of hypertension.
Methods Normotensive undergraduate students of normotensive parents (n = 40) and of hypertensive father/ mother/
both (n = 40), aged 20 – 30 years, performed serial subtraction test in a sitting position for three minutes. After taking a
rest, subjects performed cold pressor test in ninety seconds. In each test, blood pressure and pulse rate were recorded in
pre-test, during test, and post-test using an automated oscillometric device. Changes score rather than absolute scores
were analyzed using independent t-test or Mann-Whitney.
Results There were no signifi cantly differences in age, body mass index, fasting blood sugar, and plasma creatinine
between the two groups. Normotensives of hypertensive parents had signifi cantly higher offi ce systolic blood pressure
(108.33+1.6 vs 103.00+1.6 mmHg) and delta change score of cardiovascular reactivity to serial subtraction test (MABP
19.13+1.4 vs 15.5+1.0 mmHg, P= 0.04), but not to cold pressor test (MABP 24.26+1.7 vs 21.74+1.7 mmHg) than those
of normotensive parents.
Conclusion Normotensive young adults with family history of hypertension demonstrated exaggerated cardiovascular
reactivity to mental test but not to physical test. As compared to normotensive young adults without family history of
hypertension However, this familial difference in cardiovascular reactivity to mental test is confused with offi ce blood
pressure.
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Keywords
cardiovascular reactivity, cold pressor test, mental arithmetic test, of hypertension
Citation
Jenie Ikhlas M, Noor Noriah M. Family history of hypertension is associated with exaggerated cardiovascular reactivity to mental, but not to physical test. Medical Journal of Indonesia. 2010 May; 19(2): 118-124.