Molecular Docking Study on Dipeptidyl Peptidase-4 Inhibitors.
Date
2013-08
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Abstract
Dipeptidyl peptidase (DPP)-IV inhibitors are a new approach to the treatment of type 2 diabetes. DPP-IV is a member of a family of serine peptidases
that includes quiescent cell proline dipeptidase (QPP), DPP8, and DPP9. DPP-IV is a key regulator of incretin hormones, but the functions of other family members
are unknown. To determine the importance of selective DPP-IV inhibition for the treatment of diabetes, we conducted molecular docking studies on clinical inhibitors
of DPP-IV.
Description
Keywords
DPP IV, Docking, Type 2 diabetes, AutoDock
Citation
Anitha K, Gopi G, Girish, Kumar P Senthil. Molecular Docking Study on Dipeptidyl Peptidase-4 Inhibitors. International Journal of Research and Development in Pharmacy and Life Sciences. 2013 Aug-Sept; 2(5): 602-610.