Distant metastatic retinoblastoma without central nervous system involvement.
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Date
2013-07
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Abstract
Retinoblastoma is the most common intraocular malignancy in children, with a reported incidence ranging from 1 in 15,000 to 1 in 18,000 live births. Metastatic retinoblastoma is rare in developed countries, with a reported range from 4.8% in the United States to 5.8% in the United Kingdom. However, the frequency reported from developing countries varies from 9 to 11% at presentation. The mortality is very high owing to late presentations, delayed diagnosis compounded by socio-economic factors. The management of metastatic retinoblastoma is evolving, but it is still a challenge in pediatric oncology. We present a case of an extensive skeletal metastasis that initially presented as a massive orbital retinoblastoma.
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Keywords
Autologous stem cell rescue, bone marrow, metastasis, retinoblastoma
Citation
Ali Mohammad Javed, Honavar Santosh G, Reddy Vijay Anand. Distant metastatic retinoblastoma without central nervous system involvement. Indian Journal of Ophthalmology. 2013 July; 61(7): 357-359.