Anti-ganglioside antibodies in patients with Guillain Barré syndrome and other neurological disorders.
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Date
2013-04
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Abstract
A study was performed on 59 Guillain-Barré syndrome (GBS) cases, 58 neurological controls (NC) and 60 non-neurological controls (NNC) to investigate the association of anti-ganglioside antibodies in GBS and other neurological disorders. Campylobacter jejuni was isolated from 5.7% of GBS patients. Anti-ganglioside immunoglobulin G was present in 82% and immunoglobulin M in 46% in acute inflammatory demyelinating polyneuropathy patients, 70% and 44% respectively in acute motor axonal neuropathy subgroup and 38% each in acute motor sensory axonal neuropathy subgroup. Though high intensity of anti-gangliosides was present in the GBS patients, the NC patients also had adequate anti-gangliosides compared with the NNC group.
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Keywords
Anti-ganglioside antibodies, Campylobacter jejuni, electrophysiological studies, Guillain-Barré syndrome
Citation
Vaishnavi C, Behura C, Prabhakar S, Sharma A, Kharbanda P. Anti-ganglioside antibodies in patients with Guillain Barré syndrome and other neurological disorders. Indian Journal of Medical Microbiology. 2013 Apr-Jun; 31(2): 177-179.