Study on Clinico -Laboratory Profile of Children with Scrub Typhus.
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Date
2012-05
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Abstract
Scrub typhus is an acute, febrile, infectious illness caused by Orientia (formerly Rickettsia) tsutsugamushi,an
obligate intracellular gram-negative bacterium. Humans are accidental hosts in this zoonotic disease.The
present retrospective study describes clinical profile of the children hospitalized in hospital with Scrub
Typhus infection during period 2010-2011. 19 hospitalized children with clinical features suggestive
of Rickettsial disease (fever, generalized rash) who tested ELISA positive for IgM against Scrub Typhus
were included in the present study between the age of 1 years and 15 years. All children presented with
fever (100%). 42.10% had lymphadenopathy, 47.36% had eschar and 57.89% patients had cough. 26.31,
21.05%, 10.52%, had hepatomegaly, pain abdomen, and respiratory distress and gastrointestinal bleed
respectively. All of the children were investigated and treated with as per protocol. None of them died.
We think that Rickettsial infection is not quite common in this region but study showed that it is not an
uncommon entity and thus, high degree of suspicion, knowledge of geographical distribution and clinical
features of Rickettsial disease helps in its early diagnosis and treatment.
Description
Keywords
Rickettsial, Scrub Typhus, Orientia Tsutsugamushi
Citation
Jain N, Jain V. Study on Clinico -Laboratory Profile of Children with Scrub Typhus. Journal of Nepal Paediatric Society. 2012 May-Aug; 32(2): 187-192.