Congenital Anomalies at Birth: A Hospital Based Study in UAE.
Loading...
Date
2012-05
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Introduction: It is widely acknowledged that congenital anomalies heavily contribute to infant morbidity
and mortality worldwide, with an estimated 9 million infants (7% of all births) born annually having a serious
congenital anomaly that result in death or lifelong disability. The objective of our study was to estimate the
frequency of congenital anomalies at the Gulf Medical College Hospital and Research Center, Ajman and to
estimate the proportion of births with congenital anomalies per 1,000 live births. Materials and Methods:
It was a Hospital-Record based descriptive study of the 1,222 consecutive live births from December 2007
to June 2008. Results: There were 84 cases of congenital anomalies among the 1,222 live births; the rate
of anomalous births was 68.7 per 1,000 live births or 6.9%. Anomalies of the genitourinary system (40.5%)
were the most common, followed by musculoskeletal (28.6%) and cardiovascular (10.7%). Gastrointestinal,
chromosomal and multiple system anomalies accounted for 3.6% each and miscellaneous anomalies
were seen in 7.1%. Central Nervous system (2.4%) anomalies were the least. Congenital hydrocele (19.0%)
was seen to have the highest frequency amongst all recorded anomalies, followed by Talipes or Clubfoot
(14.3%). 9.3% of the male and 4.3% of the female population of live births had a congenital anomaly. Birth
Weight (p=0.005) and Gender (p=0.001) were found to have significant association with the frequency of
birth defects. Maternal Age, gravidity, parity, previous abortions, VDRL and Hepatitis B status, Gestational
Diabetes, Pregnancy Induced Hypertension, gestational age, maternal and infant blood group, nationality
and consanguinity showed no statistically significant association with congenital anomalies. Conclusion:
The proportion of congenital anomalies found in our study is alarmingly high and emphasizes the need
for more accessible nationwide screening, counseling and surveillance systems.
Description
Keywords
Congenital anomalies, congenital malformations, risk factors, maternal and infant variables, Hospital-record based, United Arab Emirates
Citation
Aryasinghe L, Moezzi D, Ansari T A, Khoury R, Mathew E, Sharbatti S A, Shaikh R B. Congenital Anomalies at Birth: A Hospital Based Study in UAE. Journal of Nepal Paediatric Society. 2012 May-Aug; 32(2): 105-112.