Clinical profile and treatment outcome of Tubercular Pleurisy in pediatric age group using DOTS strategy.
Loading...
Date
2009-10
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
A significant proportion of global tuberculosis (TB) caseload is contributed by children. Management of
pediatric TB especially EPTB is challenging. The present study was designed to study demographic, clinical profile and
treatment outcome of DOTS strategy for pediatric tubercular pleurisy.
Aim: To study the efficacy of DOTS strategy.
Methods: Retrospective analysis of 106 TB pleurisy children treated with DOTS
Results: Mean age was 10.8 years (median age 12.2 years) with more females (51.9%) than males (48.1%)c1
2=0.15;
P= 0.698 (NS). In the age group of 0-5, 6-10 and 11-14 years, there were 15.1%, 30.2% and 54.7% patients
respectively. Fever was the commonest symptom (98.1%) followed by cough (77.4%) and chest pain (55.7%).
History of contact could be elicited only in 2/3rd of cases unilateral effusion (61.3%) was commonest, followed by
empyema (22.6%), massive effusion and broncho-pleural fistula each in 13.2% cases respectively. Bilateral effusion
was seen in 3.8% cases only. Conventional methods (mantoux, radiograph, ultrasound, pleural aspiration) and minimal
invasive surgical techniques, percutaneous pleural biopsy were done to arrive at the diagnosis. Diagnosis was made by
X-ray Chest in 92.5%, exudative pleural fluid (100%) predominantly lymphocytic in 85.8%, positive AFB smear and
culture in 4.7 and 5.7% cases respectively. Category I, II and III was started on 35.9%, 2.8% and 61.3% patients
respectively. Overall treatment completion rate was 94.3%, 4.7% default rate, 0.9% failure rate and no deaths.
Conclusion: The study confirms early detection by simple tests and ensuring complete treatment using DOTS
strategy.
Description
Keywords
Pediatric Tuberculosis, Extra Pulmonary Tuberculosis, Directly Observed Treatment Short-Course (DOTS), Pleurisy, Anti-Tubercular Therapy
Citation
Sharma Sangeeta, Sarin Rohit, Khalid U K, Singla N, Sharma P P, Behera D. Clinical profile and treatment outcome of Tubercular Pleurisy in pediatric age group using DOTS strategy. Indian Journal of Tuberculosis. 2009 Oct; 56(4): 191-200.