Effects of Mangifera indica fruit extract on cognitive deficits in mice.
Loading...
Date
2009-07
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Mangos are a source of bioactive compounds with potential health-promoting activity. The present work was undertaken to
evaluate the ethanolic extract of Mangifera indica L. fruit on cognitive performances. The models used to study the effect on cognitive
performances are step down passive avoidance task and elevated plus maze task in mice. Chronic treatment (7 days) of extract and
vitamin C significantly (p < 0.05) reversed the aging and scopolamine induced memory deficits in both paradigms. Preliminary phytochemical
screening revealed the presence of free sugars, saponins, tannins, and flavonoids. The results suggest the extract contained pharmacologically
active principles that are memory-enhancing in nature.
Description
Keywords
Mangifera indica, Cognitive deficits, Vitamin C, Scopolamine, Antioxidants
Citation
Kumar Sokindra, Maheshwari Kamal Kishore, Singh Vijender. Effects of Mangifera indica fruit extract on cognitive deficits in mice. Journal of Environmental Biology. 2009 July; 30(4): 563-566.