Myocardial performance in asymptomatic essential hypertension.
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Date
2011-04
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Abstract
Prevalence, determinants, and prognostic value of left ventricular
function in subjects with asymptomatic essential hypertension are still
incompletely known. The goal of this study was to investigate the effects
of asymptomatic untreated essential hypertension on left ventricular
structure and function. The left ventricular functions were assessed among
127 hypertensive and 80 healthy subjects. American society of
echocardiography (ASE) convention was applied to measure the stroke
volume, percentage ejection fraction, percentage fractional fiber shortening,
cardiac output and cardiac index. The stroke volume, cardiac output and
cardiac index were normal but significantly high among hypertensive
compared to normotensive subjects (P<0.05). The percentage ejection
fraction and fractional fiber shortening were significantly reduced among
hypertensives compared to normotensives (P<0.05). The significant
impairment of percentage fractional fiber shortening is due to alteration in
dimension of left ventricular wall thickness, left ventricular cavity and left
ventricular geometry. This carries prognostic implication and requires further
documentations, investigations and researches. Percentage ejection fraction
and fractional fiber shortening is considered a hallmark of normal left
ventricular function. The left ventricular contractile state was negatively
correlated to left ventricular after load parameters. So the main objective
of management of hypertensive subjects should be, to reduce the after load
to improve the left ventricular contractile state.
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Keywords
left ventricular function, asymptomatic essential hypertension, echocardiography
Citation
Pandey Anil Kumar, Das Asim, Kumar Ashutosh, Babu M Sri Hari, Bhawani G, Himabindu Y. Myocardial performance in asymptomatic essential hypertension. Indian Journal of Physiology and Pharmacology. 2011 Apr-June; 55(2): 110-118.