Comparison of self-reported benzodiazepine use and urinalysis among consecutive treatment seekers at a tertiary care drug dependence treatment centre.
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Date
2010-10
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Abstract
Information provided by drug dependent patients might be
incomplete and/or discrepant. Benzodiazepines are frequently abused, but
not necessarily reported, even by the treatment seeking population. The
study aims to compare the self reported benzodiazepine use with a quick
and effective urinalysis method. A total of 51 consecutive adult patients
were included after an informed consent during their first visit to a tertiary
care drug dependence treatment centre. The socio-demographic and clinical
details were recorded on a semi-structured proforma. Patients were
specifically asked for ever, current and recent benzodiazepine use and
thereafter ten ml urine sample was collected to perform urinalysis with
cassette test for benzodiazepines. The sample, predominantly males, had a
mean age of 37.86 ±10.46 years. The common primary drugs of use were
heroin (52.9%), alcohol (23.5%) and other opioids (21.6%).Drug use was
uninterrupted in most of users (72.5%) and ranged from one to forty years.
The recent benzodiazepine use was reported by 21.6% of all users whereas
urinalysis by cassette test was positive in 50.9% of the treatment seekers.
Denial among users was 69.2% and denial among negative self report was
45%. A poor level of agreement (K) was found between results of self-report
and urinalysis for all the treatment seekers. Self report of benzodiazepine
use is highly questionable among treatment seekers. The urinalysis with
cassette test is a quick objective method which is recommended for routine
screening.
Description
Keywords
benzodiazepine cassette test, self-report urinalysis
Citation
Pattanayak Raman Deep, Jain Raka, Ray Rajat. Comparison of self-reported benzodiazepine use and urinalysis among consecutive treatment seekers at a tertiary care drug dependence treatment centre. Indian Journal of Physiology and Pharmacology. 2010 Oct-Dec; 54(4): 337-343.