Evaluation of left ventricular performance in menopausal women.
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Date
2010-01
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Abstract
The incidence of ischemic heart disease is well documented in
the literature in post menopausal women but the degree of deterioration
of left ventricular performance in estrogen deficient state in women is not
very clear. The present study was conducted to find the left ventricular
performance by recording systolic time intervals (STIs) in 50 post menopausal
women having either natural or surgical menopause and that was compared
with 25 premenopausal controls. There was significant (P<0.01) increase in
QS2-I, PEP-I and PEP/LVET ratio but significant (P<0.01) decrease in LVETI
in surgical menopause group whereas the natural menopause group
showed less increase in QS2-I (P<0.05), PEP/LVET ratio (P<0.01) and
decrease (P<0.01) in LVET-1. Thus, the performance of left ventricle is
more affected in surgical menopause group as compared to natural
menopause group. The ventricular dysfunction was observed by STIs prior
to the appearance of clinical signs and symptoms.
Description
Keywords
systolic time intervals (STIs), STI indices, left ventricular functions, menopause
Citation
Kaur Manjinder, Ahuja G K, Singh Harpreet, Walia Lily, Avasthi Kum Kum. Evaluation of left ventricular performance in menopausal women. Indian Journal of Physiology and Pharmacology. 2010 Jan-Mar; 54(1): 80-84.