When blood is thinner than water.
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Date
2013-01
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Abstract
Antagonists of vitamin K dependant clotting factors are commonly used as treatment/prophylaxis for anticoagulation. Due to their narrow therapeutic window, a wide range of complications including death may occur. International normalized ratio (INR) is monitored to measure adequacy/excess of anticoagulation. There is a plethora of risk factors that may contribute to the uncontrollably high INR values. We describe our experience of a case of deep venous thrombosis wherein the patient had an overshoot of INR during anticoagulation therapy. We review the literature and discuss management in such scenarios.
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Keywords
Anticoagulation, Bleeding, International normalized ratio
Citation
Gude Dilip, Abbas Aslam, Mohiuddin Hina. When blood is thinner than water. Annals of Cardiac Anaesthesia. 2013 Jan; 16(1): 63-65.