Evaluation of genotoxic effects in male Wistar rats following microwave exposure.
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Date
2010-06
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Abstract
Wistar rats (70 days old) were exposed for 2 h a day for 45 days continuously at 10 GHz [power density 0.214 mW/cm2, specific absorption rate (SAR) 0.014 W/kg] and 50 GHz (power density 0.86 μW/cm2, SAR 8.0 ×10-4 W/kg). Micronuclei (MN), reactive oxygen species (ROS), and antioxidant enzymes activity were estimated in the blood cells and serum. These radiations induce micronuclei formation and significant increase in ROS production. Significant changes in the level of serum glutathione peroxidase, superoxide dismutase and catalase were observed in exposed group as compared with control group. It is concluded that microwave exposure can be affective at genetic level. This may be an indication of tumor promotion, which comes through the overproduction of reactive oxygen species.
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Keywords
Catalase, Glutathione peroxidase, Micronuclei, Microwave radiation, Reactive oxygen species, Superoxide dismutase
Citation
Kumar Sanjay, Kesari Kavindra Kumar, Behari Jitendra. Evaluation of genotoxic effects in male Wistar rats following microwave exposure. Indian Journal of Experimental Biology. 2010 June; 48(6): 586-592.