Desferrioxamine-related ocular toxicity: A case report.
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Date
2012-07
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Abstract
A 29-year-old lady receiving repeated blood transfusions for β thalassemia since childhood, presented with rapidly deteriorating symptoms of night blindness and peripheral visual field loss. She was recently commenced on high-dose intravenous desferrioxamine for reducing the systemic iron overload. Clinical and investigative findings were consistent with desferrioxamine-related pigmentary retinopathy and optic neuropathy. Recovery was partial following cessation of desferrioxamine. This report highlights the ocular side-effects of desferrioxamine mesylate and the need to be vigilant in patients on high doses of desferrioxamine.
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Keywords
Desferrioxamine, ocular toxicity, optic neuropathy, pigmentary retinopathy
Citation
Simon Sumu, Athanasiov Paul A, Jain Rajeev, Raymond Grant, Gilhotra Jagjit S. Desferrioxamine-related ocular toxicity: A case report. Indian Journal of Ophthalmology. 2012 Jul-Aug; 60(4): 315-317.