Clinical profile of Group A meningococcal outbreak in Delhi.
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Date
2009-09
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Abstract
We present a retrospective analysis of clinical profile of 100 children admitted to a Government hospital at Delhi between April 2005 and December 2006 with group A meningococcal infection. Maximum children presented in late winter and spring.Younger children were less affected (5% children < 1 year). Fever (86%), vomiting (64%) and rash (63%) were the most common presenting symptoms. All children presented within 5 days of onset of symptoms and 52% within 24 hours. 67 % children had meningococcal meningitis; 20% had meningococcemia; and 13% had both. Overall mortality was 17%. Altered sensorium and shock at presentation significantly increased the mortality. All culture positive cases had group A Neisseria meningitides. All meningococcal isolates were sensitive to penicillin/ampicillin, ciprofloxacin, ceftriaxone, chloramphenicol and erythromycin except, one each resistant to ampicillin and erythromycin.
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Keywords
India, Meningitis, Meningococcemia, Neisseria, Outbreak
Citation
Jhamb Urmila, Chawla V, Khanna S. Clinical profile of Group A meningococcal outbreak in Delhi. Indian Pediatrics. 2009 Sept; 46(9): 794-796.