Letrozole as a booster therapy in growth hormone deficiency.
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Date
2009-07
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Abstract
A 13 year old boy presented to us with short stature. Evaluation revealed growth hormone (GH) deficiency. He was treated with GH replacement for 10 months and to further boost up the growth potential, an aromatase inhibitor Letrozole was added to GH therapy. After one year of combination therapy, patient had significant improvement in predicted adult height without a negative impact on pubertal progression.
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Keywords
Aromatase inhibitors, Estrogen, Growth hormone, Letrozole
Citation
Kumar KVS Hari, Jayaraman Muthukrishnan, Verma Abhyuday, Modi Kirtikumar D. Letrozole as a booster therapy in growth hormone deficiency. Indian Pediatrics. 2009 July; 46(7): 625-627.