Chronic eosinophilic leukemia with a unique translocation.
Loading...
Date
2009-06
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
We report a case of chronic eosinophilic leukemia in a 9 year old girl who presented with anemia, thrombocytopenia, leucocytosis (mostly dysplastic eosinophils), lymphadenopathy and hepatosplenomegaly. There was no increase in blasts but myelofibrosis was seen in the bone marrow. A previously unreported translocation 46,XX,t(1;4)(q24;q35), was found on cytogenetic analysis and involvement of the myocardium was also present. Shortly after commencing steroids, the family abandoned therapy.
Description
Keywords
Cardiomyopathy, Chronic eosinophilic leukemia, Hypereosinophilia, t(1;4)(q24;q35)
Citation
Arora R S. Chronic eosinophilic leukemia with a unique translocation. Indian Pediatrics. 2009 June; 46(6): 525-527.