Unexpected and abnormally low HDL cholesterol levels on combination hypolipidemic therapy.
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Date
2009-02
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Abstract
In general, Indians have low HDL cholesterol levels. Fenofibrate, a drug widely used in the treatment of
hypertriglyceridemia, usually also increases HDL cholesterol. There have been a few reports in the literature of a
paradoxical decrease in serum HDL-cholesterol in patients treated with fenofibrate, either alone or in combination
with a statin. We report three cases of paradoxical decrease in serum HDL- cholesterol in type 2 diabetic patients
treated with a statin-fenofibrate combination. ©
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Unnikrishnan R, Das R, Jaydip R, Sudhakaran C, Mohan V. Unexpected and abnormally low HDL cholesterol levels on combination hypolipidemic therapy. Journal of the Association of Physicians of India. 2009 Feb; 57(): 180-181.