Peptic ulcer disease in India - A 16 year trend analysis.
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Date
2010-10
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Abstract
Background and Aim: The incidence of peptic ulcer disease has steadily declined throughout the world. The influence of seasonal changes on the incidence of peptic ulcer disease is not
well established. The aim of the study was to identify the changing trends in the occurrence
of peptic ulcer disease from a tertiary referral center in south India and to study the seasonal
variation in the occurrence of peptic ulcer.
Methods: Retrospective analysis of the endoscopic records between the years 1989 to 2004.
Results: There was a significant decrease in the endoscopic diagnosis of duodenal and
gastric ulcers (DU and GU) over the years. Both duodenal and gastric ulcers were more
common in men than women. Over the years, there was a steady increase in the proportion of
women affected with both DU and GU. A steady increase in the mean age of endoscopic
diagnosis of GU and DU was seen over the years. The adjusted seasonal index revealed an
increase in the endoscopic diagnosis of GU and DU in the months October – March.
Conclusion: The endoscopic diagnosis of DU and GU has shown a decreasing trend over the
past 16 years. The adjusted seasonal index has shown an increasing trend between the
months of October- March.
Description
Keywords
Peptic ulcer disease, time trends, seasonal trends
Citation
Cherian Jijo Velliyappillil, Somasundaram Aravindh, Ramalingam Sivaraman, Jayanthi Venkataraman. Peptic ulcer disease in India - A 16 year trend analysis. Tropical Gastroenterology. 2010 Oct-Dec; 31(4): 260-265.