Does electrocardiography at admission predict outcome in Crimean-Congo hemorrhagic fever.
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Date
2011-09
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Abstract
Background & objectives: Crimean-Congo hemorrhagic fever is an acute viral hemorrhagic fever with considerable mortality. Despite increasing knowledge about hemorrhagic fever viruses, the pathogenesis of
Crimean-Congo hemorrhagic fever and causes of death were not well described. We aimed to evaluate whether
there were electrocardiographic parameters designating mortality among these patients.
Study design: This retrospective study was performed among confirmed Crimean-Congo hemorrhagic fever
cases in Turkey. Electrocardiography was available in 49 patients within 24 h of hospitalization. All
electrocardiograms were evaluated by two expert cardiologists according to Minnesota coding system.
Results: Among patients with available electrocardiograms, there were 31 patients who survived, and 18
patients who died of Crimean-Congo hemorrhagic fever. Both groups were similar in terms of age, sex, body
temperature, heart rate, and blood parameters. T-wave changes and bundle branch block were more frequently
encountered among those who died. Presence of T-wave negativity or bundle branch block in this cohort of
patients with Crimean-Congo hemorrhagic fever predicted death with a sensitivity of 72.7%, specificity of
92.6%, positive predictive value of 88.9%, negative predictive value of 80.6%.
Conclusions: We think within the light of our findings that simple electrocardiography at admission may help risk stratification among Crimean-Congo hemorrhagic fever cases.
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Keywords
Crimean-Congo hemorrhagic fever, electrocardiography, outcome
Citation
Yilmaz Mehmet Birhan, Engin Aynur, Bektasoglu Gokhan, Zorlu Ali, EGE Meltem Refiker, Bakir Mehmet, Dokmetas Ilyas. Does electrocardiography at admission predict outcome in Crimean-Congo hemorrhagic fever. Journal of Vector Borne Diseases. 2011 Sept; 48(3): 150-154.