Ovarian tumors with elevated ca-125 levels and severe juvenile hypothyroidism: A need for increased awareness.
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Date
2010-06
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Abstract
A 15-yr-old girl presented with bilateral gross ovarian tumors, clinical features of long-standing unrecognized
hypothyroidism and markedly elevated CA-125 levels. Ovarian resection was avoided, as the presentation was consistent
with the Van Wyk and Grumbach syndrome; and the patient was treated with replacement of thyroid hormone. Regression
of the ovarian tumors occurred 6 months after initiation of the treatment. The authors emphasise the need for increased
awareness and screening for hypothyroidism in patients with ovarian tumors, in order to prevent inadvertent operative interventions.
Description
Keywords
Ovarian tumors, Hypothyroidism, Thyroid hormone
Citation
Krishnamurthy Sriram, Seth Anju, Puri Archana, Anand Rama, Aneja Satinder. Ovarian tumors with elevated ca-125 levels and severe juvenile hypothyroidism: A need for increased awareness. Indian Journal of Pediatrics. 2010 June; 77(6): 693-694.