Treatment of autonomous ovarian follicular cyst with long-term anastrozole therapy.
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Date
2009-09
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Abstract
Functional follicular ovarian cysts are frequently reported in girls with peripheral precocious puberty (PP). These cysts are
usually self-limiting and resolve spontaneously. Several drugs like antiestrogens (tamoxifen) and new aromatase inhibitors
are seldom used for treatment. Here we report a girl with peripheral PP who presented with unilateral enlargement of the ovary
and a recurrent autonomous ovarian cyst. No skin pigmentation or bone anomaly was noted. The patient was successfully
treated with anastrozole, a highly selective aromatase inhibitor. No adverse reaction was noted. Anastrozole is a safe and
tolerable drug especially used to suppress estrogen action.
Description
Keywords
Peripheral precocious puberty, Autonomous ovarian cyst, Anastrozole, McCune Albright syndrome
Citation
Engiz Ozlem, Berberoglu Merih, Siklar Zeynep, Bilir Pelin, Ocal Gonul. Treatment of autonomous ovarian follicular cyst with long-term anastrozole therapy. Indian Journal of Pediatrics. 2009 Sept; 76(9): 950-951.