Urinary uric acid in preterm neonates.

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Date
2009-08
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Abstract
Objective. Study of uric acid level in spot urine of normal preterm AGA (appropriate for gestational age) babies in day one of their life. Methods. Spot urine samples were collected from 45 normal preterm neonates within 24 hours of their birth for estimation of uric acid. Results. The mean uric acid level was 36.50 ± 5.99 mg/dl in normal preterm neonates as compared to 18.40 ± 0.45 mg/dl in normal term babies (documented in another study) (p < 0.001). Also a significant negative linear correlation between body weight and urinary uric acid level was found { r (correlation coefficient) = – 0.970, P (probability) < 0.001}. Conclusion. Higher mean uric acid level was found in spot urine samples of preterm normal neonates than that of normal term babies on day one. Further, urinary uric acid levels were found inversely proportional to the body weight or to the gestational age (as they are AGA) of the babies.
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Keywords
Normal preterm AGA, Normal term AGA, Urinary uric acid
Citation
Basu Pallab, som Sabyasachi, Choudhuri Nabendu, Das Harendranath. Urinary uric acid in preterm neonates. Indian Journal of Pediatrics. 2009 Aug; 76(8): 821-823.